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Dalot is suspended with Amad Diallo likely to play at right wing-back with Noussair Mazraoui switching to the left flank. Leny Yoro is preferred to Harry Maguire while Andre Onana returns in goal in place of cup hero Altay Bayındır.

Manchester United return to Old Trafford on Sunday, welcoming relegation-bound Southampton. Southampton, managed by Ivan Juric, comes into this game whilst sat at the bottom of the Premier League table. However, after beating Swansea City in the FA Cup, the Reds will be hoping to bring the Saints back down to reality.

Arsenal host Manchester United in the third round of the FA Cup in the highlight fixture of this weekend's cup games.

Fernandes is a guaranteed starter after suspension, likewise Hojlund amid a lack of alternatives to lead the line. Mainoo was a bright spark off the bench against Newcastle and could be a starter as one of the No.10s, dropping deep to help Casemiro and Ugarte in the centre when United do not have the ball.

Manchester United and Southampton return to Premier League action on Thursday after their FA Cup success. Ahead of kick-off, here are the starting lineups for both clubs facing off at Old

Manchester United hope to win their first Premier League match in a month when they host last-place Southampton.