Lipid nanoparticle formulation has increased over the past two decades. LNPs have proven to be effective nano-based delivery vehicles for cytotoxic chemotherapeutic drugs, nucleic acid therapies and ...

Scientists in The Wistar Institute lab of David B. Weiner, Ph.D., have described a next-generation vaccination technology that combines plasmid DNA with a lipid nanoparticle (LNP) delivery system. The ...

Penn Engineers have modified lipid nanoparticles (LNPs) - the revolutionary technology behind the COVID-19 mRNA vaccines - to not only cross the blood-brain barrier (BBB) but also to target specific ...

From vaccines to personalized cancer therapies, scientists are studying the use of mRNA across many clinical applications. However, there are several factors that are unique to mRNA drug product ...

Malvern Panalytical’s recent peer-reviewed publication, Tailoring Lipid Nanoparticle Dimensions Through Manufacturing Processes, published in RSC Pharmaceutics, features both the NanoSight Pro ...

Lipid particles have been used in pharmaceutical developments for many years. LNPs are colloidal carriers that are submicron in size and have been developed to encapsulate pharmaceuticals while ...

Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without laboratory cell manufacturing and ex vivo expansion. The method using targeted ...

A review maps high throughput strategies that link automation, microfluidics, and barcoding into a unified pipeline, enabling faster, more predictive lipid nanoparticle development for genetic ...

ATLANTA—An oral lipid nanoparticle drug prevents tumor development in mice, suggesting this is a promising drug formulation for preventing colitis-associated cancer, according to a study led by ...