In addition, HGSOC has no early detection biomarkers and is difficult to treat. "Epithelial high-grade serous ovarian ...

Researchers at Peter Mac have uncovered potential new heredity genes that might be responsible for causing one of the most prevalent and deadliest forms of ovarian cancer. Their work is published in ...

While genetic testing rates for advanced ovarian cancer have increased, gaps in physician understanding and confidence in interpreting results may limit optimal biomarker-driven treatment and patient ...

As a result, current treatment approaches are often based on the more common high-grade serous ovarian carcinoma (HGSOC).

to characterize chemotherapy resistance mechanisms in ovarian high grade serous carcinoma. The ultimate goal of our cross-disciplinary research is to translate these multi-modal data into testable ...

Brinegar, S. Hawkins, A. Milosavljevic, M. Matzuk, and L. Yen. A recurrent BCAM-AKT2 fusion gene leads to a constitutively activated AKT2 fusion kinase in high-grade serous ovarian carcinoma. Proc ...