DOI: 10.1038/s41467-024-53933-8 XinYue Wang et al, Whole genome CRISPRi screening identifies druggable vulnerabilities in an isoniazid resistant strain of Mycobacterium tuberculosis, Nature ...

The human genome sequence generated by the private ... The microbe responsible for tuberculosis has approximately 4,000 genes. There are 100 trillion (100,000,000,000,000) cells in your body.

The search for new tuberculosis drug targets under traditional laboratory methods has historically proven to be arduous and ...

Thailand is one of 22 high burden countries of tuberculosis, and effective measures are required to control this disease urgently. Genome variation in both humans and TB bacteria may affect different ...

This test is the first qualitative real-time polymerase chain reaction (PCR) assay to combine CRISPR technology, designed to detect Mycobacterium tuberculosis (Mtb) cell-free DNA in human serum ...

Over the years they've identified several rare genetic mutations that render some people vulnerable to TB. For example, mutations in a gene called CYBB can disable an immune mechanism called the ...

DelveInsight's 'Tuberculosis Pipeline Insight 2025' report provides comprehensive global coverage of pipeline tuberculosis therapies in various stages of clinical development, major pharmaceutical ...