The indole ring system is present in many biologically active medicinal agents and natural products. Indoles are prominent structural elements in the neurotransmitter serotonin, the anti-inflammatory ...

A research group at Nagoya University in Japan has successfully developed an ultrafast and simple synthetic method for producing indole derivatives. Their findings are expected to make drug production ...

The development of drugs through chemical modifications of naturally occurring indole alkaloids has emerged as an attractive research area. However, due to their reactivity, the selective ...

Indole, and structures derived from it, are a component of many natural substances, such as the amino acid tryptophan. A new catalytic reaction produces cyclopenta[b]indoles -- frameworks made of ...

A cost-effective copper-catalyzed reaction enables selective modification at the C5 position of the indole ring, a backbone for pharmaceutical compounds. Indoles, which form the backbone of many ...

The proposed method is simple, mild, fast, and produces high yields, with the potential to inspire the development of new drugs and agrochemicals. Indolo[2,3-a]quinolizidine is a common structural ...