HCW Biologics conducted investigative study to show safe dose levels of its lead drug candidate in non-human primates that were well tolerated at ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

In an otherwise treatment-refractory population, the combination shows favorable overall response rates in patients with ...

New data suggest the potential of the CAR T-cell therapy obe-cel as a definitive treatment for R/R B-cell acute lymphoblastic ...

For the 80 million people worldwide with celiac disease, the only treatment available is to cut grains like pasta and bread out of their lives. But researchers are hoping to change that with a new ...

A new study presented reports encouraging long-term survival outcomes from an experimental viral immunotherapy, CAN-2409, in ...

Artificial intelligence (XGBoost) in predicting outcomes among CAR-T therapy patients: The impact of malnutrition and comorbidities using the National Inpatient Sample (2020-2022). Engineering ...

Rocatinlimab is also being studied for moderate to severe uncontrolled asthma, prurigo nodularis and potentially other conditions where T-cell imbalance is a root cause of inflammation. The initial ...

T cells dynamically adapt to signals in the TME, transitioning between effector, exhausted, and regulatory states. Cellular interactions, metabolic stress, and physical barriers (e.g., ECM) shape ...

Researchers at UCLA have developed a powerful new weapon in the battle against kidney cancer. Instead of relying on ...