In everyday life, our genetic material is constantly under attack from many factors. Environmental influences such as light, ...

A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...

Whenever there is a wound or infection, the body produces an inflammatory response. This is the body's first line of defense, ...

Type 2 diabetes is characterised by chronic hyperglycaemia, which disrupts the balance between reactive oxygen species production and endogenous antioxidant defences. This oxidative stress leads to ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...