Researchers found that the Wnt5a protein, secreted by inflammatory fibroblasts within cancerous tumors, inhibits angiogenesis and consequently promotes hypoxia within tumors. Hypoxic conditions help ...

The researchers treated HCT116 colorectal cancer cells — a highly aggressive type of cancer cell line — with a sub-lethal dose (2.5mM) of metformin. Using several different techniques to analyze the ...

The study found that the five-year mortality rate was significantly lower among patients who were using GLP-1 receptor ...

Gut microbes can influence the growth of colon cancer, though little is known about how they trigger the disease. A new study conducted by researchers at Baylor University Medical Center at Dallas ...

While drugs like Wegovy, Ozempic and Mounjaro are hailed for regulating blood sugar and helping people lose weight, new ...

Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide, with rising incidence linked to dietary and lifestyle changes. Despite advances in surgery and chemotherapy, ...

Scientists at Southern University of Science and Technology in Shenzhen, China, have identified a new regulator of the mammalian target of rapamycin (mTOR) pathway associated with the growth of ...

Colon cancer has been on the rise in Americans under 50 for the last three decades, but it’s not exactly clear why. Researchers suspect poor diet, obesity, sedentary lifestyles, environmental ...

Vitamin D’s anti-cancer powers go beyond bones, new findings reveal how it suppresses inflammation, boosts immune surveillance, and disrupts tumor development to guard against colorectal cancer. Study ...

In healthy colon tissue, "good" fibroblasts help support tissue architecture. However, in colon cancer, these fibroblasts transform into "bad" fibroblasts in low-oxygen areas near the tumor surface.