This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Background Heart failure (HF) remains associated with high mortality worldwide despite advances in guideline-directed therapy ...

Heart failure with preserved ejection fraction (HFpEF) accounts for nearly half of all heart failure cases and remains a major clinical and therapeutic challenge. Despite having preserved systolic ...

Compensated heart failure involves heart failure that causes minimal symptoms. Decompensated heart failure refers to heart failure that has progressed, leading to a worsening of symptoms. Heart ...

Mineralocorticoid receptor antagonists (MRAs) are a cornerstone of treatment for patients with chronic heart failure and reduced ejection fraction. In international guidelines, these agents have a ...

Deaths from cardiac conditions like heart failure, high blood pressure, and heart rhythm disorders are on the rise, a new study finds. Overall heart disease deaths rates have dropped 66 percent over ...

Chronic diseases such as diabetes, heart disease, high blood pressure, arthritis and certain types of cancer are leading ...