Chemokines, acting as "traffic controllers" in the tumor microenvironment, regulate immune cell infiltration and local ...
Chemokine Receptor 5 (CCR5) is a G-protein coupled receptor long recognised for its role in immune cell trafficking and as a co-receptor for HIV. However, increasing evidence over recent years has ...
Scientists at St. Jude Children’s Research Hospital report that they have identified a way to improve CAR T-cell homing for osteosarcoma. Their study “Redirecting B7-H3.CAR T cells to chemokines ...
Researchers at the VIB-UGent Center for Medical Biotechnology have discovered a promising strategy to improve treatment responses in multiple myeloma patients by blocking a protein that plays a key ...