Researchers have identified the interferon-stimulated protein IFIT3 as a highly dysregulated centromere-proximal protein in ...

The centromere is necessary for the transport of chromosomes during cell division and, therefore, for the correct transmission of genetic information. Most plants and animals have chromosomes with a ...

Chromosome-level genomes of holocentric nutmeg and monocentric ylang-ylang reveal that lineage-specific repeat and epigenetic ...

Holocentric chromosomes have evolved independently from X-shaped monocentric chromosomes multiple times in both animals and plants, but the mechanism behind the centromere-type transition is unknown.

On the X-shaped chromosome, the centromere is at the “cross” point of the two arms. Like the rest of the chromosome, centromeres are composed of double-stranded DNA and protein. Centromeres play an ...

Centromeres are curious structures. These specially organized chromosomal regions are best known for their unique and critical role in cell division, in which they are well understood to serve as the ...

Researchers have made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides. Mistakes in ...

Without centromeres, cells cannot divide properly and the overall process of mitosis fails. Why are these small chromosomal regions so essential to such a major cellular process? With a few exceptions ...

About a third to two-thirds down the shaft of a chromosome is a constricted site called the centromere. When a chromosome replicates, the old and new pair (called chromatids) are held together at this ...

When scientists announced the complete sequence of the human genome in 2003, they were fudging a bit. In fact, nearly 20 years later, about 8% of the genome has never been fully sequenced, largely ...