T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by ...

Natural Killer (NK) cells are vital immune defenders that target and destroy cancer cells. However, in aging and cancer patients, NK cells often become "senescent"—losing their effectiveness due to ...

Tumors are stressful places for cancer-fighting immune cells. Low oxygen, high acid levels, and other stressors put strain on ...

T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by ...

Aging is a complex biological process characterized by the progressive decline of physiological integrity, leading to impaired function and increased vulnerability to disease. It is the strongest risk ...

Every cell in the body normally has its fixed place as part of a tissue structure. Except for a few cell types, such as blood or immune cells. But cancer cells also cross established boundaries, grow ...

Cellular senescence is a process in which the cell cycle becomes permanently arrested, thereby inhibiting cell division, proliferation and growth. Various cellular stresses, such as DNA damage, ...

Chromosomes are structures made of protein and DNA code, and would unravel and lose proper function without the telomeres ...

Could a keto diet affect males differently from females? A study from The University of Texas Health Science at San Antonio (UT Health San Antonio) suggests so, and estrogen could promote different ...