Embryonic development is one of the most dynamic biological processes in nature. Cells and tissues organize and reorganize ...

Phosphoinositides are a family of membrane lipids distinguished by phosphate groups at specific positions on the inositol ring, acting as spatial and temporal organisers of cell activity. Through ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Our body receives and processes a vast number of signals. Chemical signals serve as guidance cues and ensure, for example, ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...

Calcineurin is a ubiquitous serine/threonine phosphatase that decodes calcium signals to regulate an array of cellular functions. Its activation requires calcium binding to calmodulin and the ...

Within the past decade, biologists have discovered that one strategy cells use to keep their contents organized is a ...

A team led by Stanford biologist Bo Wang and lead author Chew Chai has identified a previously unknown type of immune cell in ...

Ribosomes don’t just make proteins—they can sense when something’s wrong. When they collide, they send out stress signals that activate a molecule called ZAK. Researchers uncovered how ZAK recognizes ...

The distinct aging rates of neural progenitor cells and Wnt signaling dictate mammalian cortical layer proportions.

Researchers at the Keck School of Medicine of University of Southern California (USC) have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response ...