Most potential oncology drugs fail during the drug development pipeline, even when there has been promising data for their efficacy during the in vitro stage. This makes it vital to identify in vitro ...

Scientists have been peeking through microscopes and taking pictures of cells for decades. The methods available for visualizing highly complex cells have changed over time, moving from simpler ...

Cell Painting and Cell Impermeant Dye-based Assay Distinguish Effector from Target Cells One of the functions of the immune system is to recognize and destroy targets. This is accomplished by effector ...

This article is based on a poster originally authored by Felix L-Perusse, Josiane Bourque, Martin Cottet, Simon Mathien, and David W. Andrews, which was presented at ELRIG Drug Discovery 2024 in ...

The advent of sophisticated cellular imaging techniques, combined with technological advances in automation and data collection and interpretation, has provided the basis for the development of ...

A team led by researchers at Baylor College of Medicine has identified flavonoids, natural compounds found in plants, that are toxic to bladder cancer cells cultured in the lab. The researchers report ...

Modern day drug discovery is shifting from single end point assays to more complex phenotypic assays that query single cell and population responses to chemicals and genetic manipulation. One such ...

WALTHAM, Mass.--(BUSINESS WIRE)--PerkinElmer, Inc., a global leader committed to innovating for a healthier world, today launched the first cell painting kit as part of its new portfolio of PhenoVue™ ...

CARLSBAD, Calif.--(BUSINESS WIRE)--Life science researchers who want to expand their capabilities beyond traditional cell counting instruments can now do so with the Countess II FL, a next-generation, ...

The New Assay for the Human Glucagon-Like Peptide-1 Receptor (GLP-1R) is for Preclinical Research of Type II Diabetes and Obesity. "A reliable GLP-1R assay is essential for researchers studying type 2 ...