Bone tissue engineering seeks to restore structural and functional integrity by emulating the instructive role of the extracellular matrix (ECM). Strategies derive from decellularized matrices, ...

Bone cells called osteocytes help maintain skeletal strength, but how newly formed osteocytes survive remains unclear.

Researchers found that FGFR1 signaling helps organize bone-building material and cellular connections needed for newly ...

A new study of the PhyloBone project of the University of Turku, Finland, identifies hundreds of non-collagenous proteins in the bone matrix that may play regulatory roles in bone formation and ...

Tumor cells are known to be fickle sleeper agents, often lying dormant in distant tissues for years before reactivating and forming metastasis. Numerous factors have been studied to understand why the ...

Osteoporosis is a common disorder, especially in the elderly, characterized by bone loss and increased fracture risk. Treatments target abnormal osteoclast activity but face adherence issues. The ...

A mouse study finds that the collagen receptors β1 integrin and DDR2 cooperate to drive skeletal progenitor cell migration, proliferation and differentiation during cranial bone repair.

Newswise — Extracellular vesicles (EVs) secreted by adipose-derived stem cells (ADSCs) have emerged as a promising cell-free therapeutic tool for bone regeneration. These EVs deliver a diverse array ...

A mouse study finds that constitutive HIV-1 viral protein expression, without viral replication or antiretroviral drugs, is ...

Wif1 overexpression accelerated osteogenic differentiation by activating genes related to late-stage osteogenic differentiation and mitophagy processes. Moreover administering Wif1-overexpressing ...