Croucher said the research uncovered new therapeutic opportunities against not only bone disease but also cancer. "Bone is the main hiding place for dormant cancer cells and a common site of relapse, ...

New knock-in mouse models of hypophosphatasia show that specific ALPL gene variants shape dental symptoms independently of ...

Seven out of 10 American women will have osteopenia or osteoporosis in their lifetime, and statistics show that bone conditions predominantly affect women more than men, especially menopausal and ...

It is hoped the discovery will enable the development of new therapies to rebuild lost bone, offering hope to almost half of all individuals over 50 living with rare and common skeletal conditions ...