The maxillary and mandibular bones undergo high-turnover remodeling to maintain mechanical competence. Common dental or periodontal diseases can increase local bone turnover. Bisphosphonates (BPs) ...

Osteoporosis weakens bones by reducing density, but bisphosphonates can help preserve strength by slowing down bone loss. Bisphosphonates are drugs made from synthetic compounds that resemble natural ...

Bisphosphanates are used primarily for the prevention and treatment of osteoporosis, and are also indicated for osseous complications of malignancy. In addition to their bone resorption properties, ...

Bisphosphonates are medications that used to treat bone loss and are the most common agent to be prescribed for osteoporosis. These drugs can also reduce fracture risk in cases of previous fracture.

In a shift from previous recommendations, the American College of Physicians (ACP) now recommends that clinicians only use bisphosphonates (alendronate, ibandronate, risedronate, zoledronate) for ...

Bisphosphonates are the mainstay of osteoporosis therapy. Extensive clinical evaluation supports their utility in stemming progression of the disease and in reducing fracture risk. In the course of ...

Bisphosphonates are biological analogues of naturally occurring pyrophosphates, by-products of adenosine metabolism, and were developed after the discovery that these nonmetabolized compounds have a ...

The unprecedented coronavirus disease 2019 (COVID-19) pandemic facilitated the rapid development and subsequent deployment of several novel and highly effective vaccines. However, the role of ...

Denosumab is a different type of medicine. It's a type of bone targeted treatment called a monoclonal antibody. You might have this as a treatment for cancer that has spread to the bones. It helps to ...

Bisphosphonates, which are used to treat osteoporosis and prevent fractures, are increasingly being used more effectively in a population more likely to benefit, according to results presented at ENDO ...

These significant correlations are profound and intriguing, because they suggest that bisphosphonate-induced changes to the microenvironment surrounding potential cancer cells can be exploited in ...

So what sets this trial apart from the others? This study evaluated the utility of the second-generation bisphosphate pamidronate disodium as adjunctive therapy. Unlike many of the other trials ...