Tumors are stressful places for cancer-fighting immune cells. Low oxygen, high acid levels, and other stressors put strain on ...

Early findings showed EXG-34217 elongated telomere length ex vivo. The Food and Drug Administration (FDA) has granted Orphan Drug designation to EXG-34217 for the treatment of telomere biology ...

Reporting in Nature, scientists have identified a novel process that protects the ends of chromosomes from incorrectly applied DNA repair.. | Cell And Molecular Biology ...

This paper, published in December 1994, describes a polymerase chain reaction (PCR)-based assay for measuring the activity of telomerase, the enzyme that controls telomere length. But more important, ...

New research published in Immunity by researchers at the University of Pittsburgh found that, in mice, the toxic tumor ...

Increased chromosomal instability impairs oocyte quality, contributing to female reproductive aging. The telomeric DNA damage ...

Vitamin D is one that has found itself in the spotlight often in recent years. Also known as the "sunshine vitamin", it has ...

Data published in NEJM Evidence detail the first clinical test of ZSCAN4 for telomere elongation. Treatment with EXG-34217 resulted in in vivo telomere elongation in a subpopulation of lymphocytes to ...

Spaceflight accelerates aging in blood stem cells, raising health risks for astronauts and offering insights into human aging ...

In vitro findings reveal Telomir-1's dual action: targeting DNA methylation switches and cutting into the Wnt "fuel line" ...

Edited by: Karen Young Kreeger C.M. Counter, J. Gupta, C.B. Harley, B. Leber, S. Bacchetti, "Telomerase activity in normal leukocytes and hematologic malignancies ...