Tokyo, Japan – Researchers from Tokyo Metropolitan University have studied pancreatic islet cell loss in people with no previous pancreatic problems. They identified key trends in the types of cells ...

A partially purified secretory granule fraction, isolated from rat islets of Langerhans by differential centrifugation, was used for investigating the stability of the beta granules during incubation ...

Researchers at Karolinska Institutet have established a novel transplantation site for islets of Langerhans that enables long-term intravital microscopy of islet physiology in awake mice with ...

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance, published in ...

Detailed characterization of human pancreatic islets is key to elucidate the pathophysiology of all forms of diabetes mellitus, including its most common form known as type 2 diabetes (T2D). However, ...

Researchers have carried out pioneering efforts to optimize the functionality of pancreatic cells produced from stem cells. In a new study, the group has demonstrated that stem cells can form cells ...

The beta cells of the pancreas don’t need the assistance of other pancreatic cells to produce insulin, according to new research. The findings are not only a potential game-changer for diabetics, but ...

Wenzhou Medical University researchers have reimagined the spleen as a viable site for islet transplantation, enabling long-term diabetes control without the burden of full immunosuppression.

Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimislecel ...