Processes yielding >500 mg plasmid DNA/L have previously been reported by Merck, Boehringer Ingelheim, and Nature Technology (NTC). Common features among these high-yield processes include the use of ...

Batch fermentation was used during World War II to produce industrial solvents for ammunition production. Small amounts of hydrogen produced early in the fermentation process were not recovered.

While industrial bioprocesses have been operated in fed-batch mode for a long time, the screening of high-producer cell lines and a lot of other development work is still performed in batch mode for a ...

Online process analytical technology (PAT) has grown in popularity in the biotechnology industry in recent years. Many fermentation scientists have been using Thermo Scientific™ process mass ...

So, you have a great idea for a new fermentation-based product or ingredient, and a successful process in the lab. All that remains is to scale up to mass production. That’s just a matter of running ...

Fermentation monitoring has reached a point of quiet convergence with pharmaceutical manufacturing: the same Raman probe measuring glucose and lactate in a biopharma bioreactor is now deployed inside ...