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WEBRare Disease Companion (RDC) is a network of news and information websites that supports people living with rare diseases. Through accurate, authentic, and compassionate news coverage, feature-length articles, and patient-friendly educational material, RDC provides insights into living with rare diseases at every point along the patient journey.
Testing and diagnosis of HDFN - HDFN Companion
WEBDiagnostic tests before birth. The tests that can be used to diagnose HDFN before a baby is born include amniocentesis, ultrasound, and blood tests on the mother or the umbilical cord.. Blood tests. A blood test can be done on blood drawn from a pregnant woman to see whether she has antibodies against the red blood cells of her baby.
About HDFN Companion
WEBHDFN Companion is part of Haymarket Media’s Rare Disease Companion network of websites, which fills the wide informational gaps that exist for rare disease patient communities on the web. HDFN Companion provides mothers who have the HDFN diagnosis and their families with news, educational materials, and trustworthy insights that give them the ...
What is HDFN? - hdfncompanion.com
WEBHemolytic disease of the fetus and newborn (HDFN) is a disorder in which a pregnant woman’s immune system attacks her baby’s red blood cells, leading to their destruction and resulting in severe anemia, also known as erythroblastosis fetalis.In severe cases, HDFN can be associated with permanent damage to the baby’s brain or even death before the baby is born due to high levels of ...
The role of genetic testing and counseling in HDFN
WEBSep 9, 2024 · The most common cause of HDFN is a Rh incompatibility in which the mother is RhD-negative and the fetus RhD-positive. In recent decades, the sysematic administration of Rh(D) immunoglobulin to RhD-negative pregnant women has dramatically reduced the incidence of RhD-associated HDFN.. However, if the fetal genotype is not RhD-positive, the administration of Rh(D) immunoglobulin is unnecessary.
Treatment and care of HDFN
WEBIn some cases, the baby may be delivered early, as babies with severe anemia may not tolerate labor well.. Postnatal treatment. The treatment of HDFN after birth includes phototherapy, intravenous fluids, intravenous immunoglobulin (IVIG) and exchange transfusion. All of these treatments attempt to reduce the levels of bilirubin—a byproduct of the breakdown of red blood cells, which can ...
A guide to cord blood banking and HDFN
WEBDec 29, 2023 · Cord blood is the blood that remains in the placenta and the umbilical cord following a baby’s birth. The rope-like structure known as the umbilical cord connects the mother to the unborn baby throughout a pregnancy. Once the baby is born, the placenta is usually discarded, together with the cord blood that is contained within it.
Prognosis of HDFN - HDFN Companion
WEBBefore their introduction in 1968, the death rate of babies affected by HDFN was around 50%.The rate dropped to 0.5% after the introduction of the injection.
What is plasmapheresis and how can it treat HDFN? - HDFN …
WEBAug 9, 2024 · Plasmapheresis, also known as plasma exchange, is used to treat a variety of conditions, including autoimmune diseases, blood toxins, neurological diseases and high levels of cholesterol. In HDFN-affected pregnancies, it involves extracting the mother’s blood and separating the plasma, which includes …
HDFN causes and risk factors - HDFN Companion
WEBBlood types and Rh factors. Mismatches that cause HDFN can be between the blood types (A, B and O) and/or Rhesus (Rh) factors, a protein that can be found on the surface of red blood cells.. ABO incompatibility. ABO incompatibility occurs when the blood type of the mother and that of the baby do not match.