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WEBSep 12, 2024 · eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
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WEBeLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in …
How to measure and evaluate binding affinities | eLife
WEBAug 6, 2020 · Quantitative measurements of biomolecule associations are central to biological understanding and are needed to build and test predictive and mechanistic models. Given the advances in high-throughput technologies and the projected increase in the availability of binding data, we found it especially timely to evaluate the current standards for ...
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WEBMar 11, 2019 · eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
The Natural History of Model Organisms: The secret lives of
WEBJun 4, 2015 · Drosophila: D. hydei (the larger, dark flies) and D. melanogaster and D. simulans (the smaller, lighter flies) interacting at a food source. Although there is little sexual dimorphism between males and females of the D. hydei species, males can be distinguished in the video because they approach other flies to court. In the D. melanogaster and D. simulans species, males are smaller than the ...
Sensitive red protein calcium indicators for imaging neural activity
WEBMar 24, 2016 · Neurons encode information with brief electrical pulses called spikes. Monitoring spikes in large populations of neurons is a powerful method for studying how networks of neurons process information and produce behavior. This activity can be detected using fluorescent protein indicators, or “probes”, which light …
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Sodium taurocholate cotransporting polypeptide is a functional …
WEBNov 13, 2012 · Liver diseases related to the human hepatitis B virus (HBV) kill about 1 million people every year, and more than 350 million people around the world are infected with the virus. Some 15 million of these people are also infected with the hepatitis D virus (HDV), which is a satellite virus of HBV, and this places them at an even higher risk of liver diseases, including cancer.
Genetic code expansion, click chemistry, and light-activated PI3K ...
WEBAug 20, 2024 · Receptor tyrosine kinases (RTKs) are the second largest class of cell surface receptors, with 58 members in the human genome (Robinson et al., 2000).Binding of agonists, typically polypeptides such as growth factors, to their extracellular amino-terminal domains results in autophosphorylation of their intracellular carboxy-terminal domains (Lemmon and Schlessinger, 2010).
Science Forum: SARS-CoV-2 (COVID-19) by the numbers - eLife
WEBMar 31, 2020 · The COVID-19 pandemic has made brutally clear the need for further research into many aspects of viruses. In this article we compile data about the basic properties of the SARS-CoV-2 virus, and about how it interacts with the body ().We also discuss a number of questions about the virus, and perform 'back-of-the-envelope' calculations to show the insights that can be gained from knowing some ...